This is really up to you.. I know this a very vague answer, but the truth is I have seen some Drop Ship Lifestyle students sign up and make their first sale within two weeks because they were working crazy hours to get everything set up, and I've seen some take months to make it happen.
If you're coming into this with no prior experience, my guess would be that you should be ready to invest about 50 - 60 hours to following along with our course.
This should be enough time to brainstorm niches, do your market research, build your demo store, get approved with some suppliers, have them uploaded to your site, and start getting some traffic.
Alternatively, you could outsource the web design work to our team (this is the part of the process with the biggest learning curve), and that would likely cut off 10+ hours of time.
I know it all sounds like a lot of work upfront, but the payoff is worth it! After you're all set up you should be able to manage your store in less than an hour each day.